Recent Progress of On-line Sample Preconcentration in Capillary Electrophoresis

Based on the introduction of online sample preconcentration technology, such as stacking, pH junction, sweeping, isotachophoresis and chromatography in capillary electrophoresis, some novel studies on this technology from 2007—2008 year were reviewed. It is pointed out that the combination of two or more than two preconcentration methods, the improvement of the original preconcentration method and the novel enrichment method based on novel principle would be the direction of online sample preconcentration research in the future. Furthermore, the higher sensitivity in less time together with simple and reproducible operation, and without any offline pretreatment for complex samples should be focused on establishing new methods. 83 references were cited.