Distribution Characteristics of 29 Antibiotics in Groundwater in Harbin

MA Jian-sheng; WANG Zhuo; ZHANG Ze-yu; LIU Qiang; LI Li-jun

doi:10.15898/j.cnki.11-2131/td.202101040001

Rock and Mineral Analysis > 2021 > 40(6): 944-953. > DOI: 10.15898/j.cnki.11-2131/td.202101040001

MA Jian-sheng, WANG Zhuo, ZHANG Ze-yu, LIU Qiang, LI Li-jun. Distribution Characteristics of 29 Antibiotics in Groundwater in Harbin[J]. Rock and Mineral Analysis, 2021, 40(6): 944-953. DOI: 10.15898/j.cnki.11-2131/td.202101040001

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Distribution Characteristics of 29 Antibiotics in Groundwater in Harbin

Shenyang Centre of Geological Survey, China Geological Survey, Shenyang 110032, China

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Received Date: January 03, 2021
Revised Date: May 25, 2021
Accepted Date: July 27, 2021
Published Date: November 27, 2021

Abstract

HIGHLIGHTS
(1) The content and distribution of typical antibiotics were explored by the collection and testing of groundwater in Harbin.

(2) Typical antibiotics were detected mainly in densely populated areas in the south central and eastern parts of the city in groundwater.

(3) The discharge of pharmaceutical factories, animal husbandry and urban sewage has a significant impact on the distribution of antibiotics in groundwater.

ABSTRACT

BACKGROUNDAt present, the supervision of antibiotic abuse and its research is being strengthened. In recent years, antibiotics have been detected in varying degrees in water in central China. This reinforces the concern of the pollution of antibiotics in surface and groundwater.
OBJECTIVESTo investigate the distribution characteristics of 29 antibiotics in groundwater in Harbin.
METHODSA total of 26 groups of groundwater samples were collected in Harbin, and the sampling scope included habitation and production areas such as densely populated, industrial production, agricultural districts and animal husbandry. The ultra-performance liquid chromatography-triple quadrupole mass spectrometry method was used to analyze 29 kinds of antibiotics covering six types, including sulfonamides, quinolones, macrolides, β-lactams, tetracyclines, and lincosamides.
RESULTSAntibiotics in the groundwater of Harbin were mainly composed of sulfonamides, quinolones, macrolides and tetracyclines and the detection rates were 61.5%, 46.2%, 42.3% and 38.5%, respectively. The content of antibiotics detected ranged from 0.02 to 681ng/L, and the highest contents of sulfathiazole, sulfadiazine, and lincomycin were more than 100ng/L. The average content of quinolones was low compared with some domestic and international areas (such as Beijing, Tianjin, and Barcelona). Sampling sites with higher antibiotic levels were mainly found in the central, southern and eastern regions of the city. These areas are also relatively densely populated and are generally distributed around pharmaceutical factories, urban sewage outlets, and poultry and livestock farms.
CONCLUSIONSThe distribution characteristics of antibiotics in groundwater in Harbin are strongly related to the impact of human production and living activities.
- groundwater,
- antibiotics,
- quinolones,
- space distribution,
- ultra performance liquid chromatography-triple quadrupole mass spectrometry

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