Abstract: The Kuimeishan tungsten deposit is located in the junction area of the eastern segment of the E-W-trending Nanling tectonic zone and southern segment of the NE-NNE trending Wuyishan tectonic zone. It is characterized by intergrowth of quartz vein-type wolframite and skarn-type scheelite in Dingnan county, south of Jiangxi province (Gannan). However, there is no accurate chronological evidence to confirm whether the metallogenesis occured in the Yanshanian period. The SHRIMP U-Pb age of zircons obtained from the metallogenic biotite granite is (157.7±2.7) Ma (n=11, MSWD=1.9), and the Re-Os isochron age of molybdenite from the ore-bearing quartz veins is (153.7±1.5) Ma (n=5, MSWD=0.16). The accurate metallogenic and diagenetic chronology results indicate that the Kuimeishan tungsten deposit was formed during the large-scale diagenesis and mineralization of tungsten ore in the Mesozoic period that occurred in South China. Based on the ‘five levels+basement’ prospecting model and the latest prospecting clues, it is possible that new ore bodies are amassed in the contact zone of deep rock body in Kuimeishan, which has great potential for prospecting. It is significant to the deep and periphery prospecting for tungsten as we proposed the possibility of skarn type tungsten which occurred nearby the deep and periphery part of quartz vein type tungsten in the Gannan region.