Abstract: There is no available petrogenic chronology data at present for the Bai'e granitic pluton, which is located in the Yushan metallogenic belt of South Jiangxi, This paper firstly attained its two groups of petrogenic ages, (174.1±5.4) Ma and (152.4±1.4) Ma by means of the Laser Ablation-Multicollector Inductively Coupled Plasma-Mass Spectrometry (LA-MC-ICPMS) method, which shows that it had experienced two periods of tectonic-magmatic activity at intervals of 22 Ma. The former occurred in the second stage (170-180 Ma) of the early Yanshanian era, while the latter occurred in the third stage (150-165 Ma). Combining obtained achievements, the author considers the forming of the Bai'e granitic pluton to be related to lithosphere extension and partial melting of the continental crust resulting from crust-mantle interaction after Indosinian orogeny. Both of the magmatic activities occurred within the stages of large-scale metallogeny in southern China, which indicates their favorable ore prospecting perspective. The second time of tectonic-magmatic activity points to more potential in metallogeny due to the contribution of peak metallogeny in the Nanling area, especially that of W and Sn in southern Jiangxi. Additionally, the Bai'e granitic pluton may have experienced Indosinian magmatic activity according to information from other plutons in the Yushan metallogenic belt.