Abstract: Computer and local area network were used in quality control of analytical data for regional geochemical samples. Excel software in Microsoft Office was used for quality control by evaluating and estimating the quality of analytical data of different items and elements in both inner quality control and standard reference samples. The computerized quality monitoring and control system includes Access database, quality control tables of standard reference samples, quality control tables of cryptogrammic checkup, chart of quality monitoring and control, print of detection reports and etc.. The system has been applied to the quality control in analysis of regional geochemical samples.