Abstract: The Dazhuyuan bauxite deposit is one of the most important deposits discovered during recent decades, and the Wuchuan-Zheng'an-Daozhen bauxite area (simplified as Wuzhengdao area) has also been listed as one the first uncompartmentalized prospecting areas on the national level. In order to promote prospecting, it is urgent to summarize the characteristics of the Dazhuyuan typical deposit and the regional ore-forming condition and outline the metallogenic regularity for the Wuzhengdao bauxite area. Based on the analysis of ore-bearing strata, structure, paleoclimatology, palaeogeomorphology and palaeogeography, the distribution of ore-bearing strata (the Dazhuyuan Formation, C₂d), the existence of ore-source strata (Hanjiadian Formation, S₁hj), the dissolution of limestone from the basement (the Huanglong Formation, C₂h), and the stable stretching of syncline are identified as the most four most important key-points for the further prospecting of bauxite deposits in this area. The Liyuan-Luchi syncline, the Zhangjiayuan syncline, the Datang syncline, the Xinmo syncline, the Daozhen syncline, the Taoyuan syncline, the Anchang syncline and the Huanxi syncline have also been chosen as the main targets for uncompartmentalized prospecting and ore-genetic models for different kinds of bauxite deposits have been built, clearing the key exploration prospecting direction. Since 2012, three superlarge-scale, four large-scale and three middle-scale bauxite deposits have been discovered and about 470 million ton of bauxite have been confirmed, which show a remarkable result of uncompartmentalized prospecting in the Wuzhengdao area, North Guizhou. The regularity and ore-genetic model for bauxite deposits, based on practice, can provide scientific evidence for uncompartmentalized prospecting and further exploration in the Wuzhengdao area.